Tuesday, August 28, 2012
Low Vitamin D, Epstein-Barr, Linked to Later MS
Nutri-GenX LC Pioneered the Field of Epigenetic Nutrition and Wellness
Epigenetics is the only hope that the human race has for survival today if we do not curb the epidemic rise in Diabetes, Obesity, Cancer and Immune diseases. At Nutri-GenX we have centered our research and development around Anti-aging, Anti-stress and what we believe to be the Environmental toxins that have set us upon this deadly course. We understand genetics, polymorphisms and environmental factors that make choosing the right nutritional supplement critical in today's stressful, toxic environment. 80% of the Worlds adult population today is clinically deficient in one or more critical nutrients that will have a negative impact on the quality of their lives as they age.
Epigenetics "our past + our genes" carry the answers so this dismal outcome doesn’t have to happen to you or your loved ones. because you now have a choice to improve your health, your children and your grandchildren. Supplementation is painless and by far the cheapest health insurance in the world at only pennies a day. Why risk the misery and expense of a preventable long term Illness or nutritional disease like obesity, diabetes or cancer. These are just a few of the preventable diseases that can rob you of your health, vitality and quality of life as you age.
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The following article is an example of what we are talking about in the field of epigenetics today. Vitamin D deficiency leads to a higher incidence of contracting Epstein-Barr virus if exposed and that is linked to contracting MS later in life. That's all from a deficiency in Vitamin D.
From Medscape Medical News > Neurology
Low Vitamin D, Epstein-Barr, Linked to Later MS
"Changes [in both] vitamin D levels and EBV immunoreactivity even 2 to 3 years prior to the first clinical disease manifestation appear to be associated with clinical breakthrough. So we are looking at 2 factors together several years before the first symptoms and signs of MS," study author Andrew Chan, MD, from St. Josef-Hospital, Ruhr-University, in Bochum, Germany, told Medscape Medical News.
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Dr. Andrew Chan
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"I believe it is safe to say that both factors are associated with clinical disease breakthrough, possibly within a relatively restricted interval," said Dr. Chan. Whether they are independent risk factors that are amenable to intervention remains to be seen, he added.
The study was published online August 11 in Journal of Neurology, Neurosurgery & Psychiatry.
Low Vitamin D
The analysis included 56 blood samples donated by 25 patients in Germany (21 female; mean age, 31.5 years at time of donation; 33.4 years when they developed MS).
Researchers obtained serum samples from 18 of the 25 participants after an MS diagnosis was established, and collected 39 serum samples from 25 age- and gender-matched healthy blood donors.
From these samples, researchers investigated both 25-hydroxyvitamin D (25-OH-D) serum levels and immunoglobulin C (IgC) response against the EBV nuclear antigen-1 (EBNA1).
EBNA1 is important for establishing and maintaining the altered state of cells following infection with EBV, according to Masaaki Niino, MD, PhD, director, Department of Clinical Research, Hokkaido Medical Center, Sapporo, Japan, who contributed a related editorial. The risk for MS increases more than 7-fold with increasing titers of anti–EBNA1 IgC antibodies, he said.
Cross-sectional analyses revealed a gradual decrease in 25-OH-D levels during the pre–clinically isolated syndrome (CIS) phase. This change was particularly evident during the 24 months before CIS (median, 47.8 mmol/L vs 81.6 mmol/L for healthy controls; P = .004).
Not an Isolated Finding
After an MS diagnosis was established, levels were strongly reduced — median, 24.5 mmol/L (P < .0001) — compared with those of pre-CIS sera (57.1 mmol/L) or healthy controls.
In contrast, IgC response against EBNA1 was increased during the pre-CIS phase compared with that of healthy matched blood donors. The most pronounced alterations were seen in the 36 months before clinical manifestation (median, 185.9 IU/mL vs 63.7 IU/mL for healthy controls; P = .002).
Reverse causality — long-standing disease processes causing changes in 25-OH-D and EBNA1 status — cannot be excluded, according to the authors.
Although the current study did not detect any direct relationship between 25-OH-D levels and EBNA1 immunoreactivity, some previous experimental data did suggest that the 2 factors may work synergistically, said Dr. Chan.
"For example, vitamin D may influence the immune reaction to EBV."
Dr. Chan hypothesized that the influence of vitamin D on EBV immunoreactivity or on other adaptive immune responses could be especially important during the interval highlighted in the study.
Larger studies are needed to address this issue, he said.
The study included only white patients living in Germany, but its results are compatible with those from other studies from different geographic regions, said Dr. Chan. "I would guess that this is not an isolated finding."
Dr. Chan cited another very large study — conducted with samples from US military staff — that linked lower vitamin D levels with higher risk of developing MS later in life.
"However, in their study, vitamin D levels before the age of 20 [were] important, whereas we saw profound changes a couple of years prior to disease onset," said Dr. Chan.
"Whereas the cohorts can't be directly compared because of selection bias, size, etc, I believe the datasets complement one another, and that our results are hypothesis-generating," he added.
The current study combined results for men (only 4) and for women, so it is possible that the results may be gender-specific. However, Dr. Chan and colleagues addressed the issue of sex differences by using gender/age-matched controls.
The study used samples that dated back several years but, according to Dr. Chan, it is unlikely that it would be possible to track the association back any farther.
"While we were able to obtain samples up to 7 years prior to disease manifestations, many blood donor centers do not keep samples for very long intervals for logistical reasons. Most of the centers we contacted kept the samples for about 5 years. Therefore, it is very difficult to track down even earlier time points."
Among the drawbacks of the study were its limited sample size, possible recall bias, and inability to dissect determinants of individual vitamin D levels, including sunlight exposure and diet.
Need for Research in Diverse Populations
In his commentary, Dr. Niino said that the study helps answer the question of whether long-term low vitamin D levels and indication of remote EBV infection are associated with risk factors for developing MS.
"These findings suggest that the 2 major risk factors of low vitamin D level and remote EBV infection are important, especially during the few years prior to clinical manifestation."
Dr. Niino also noted that vitamin D levels — or at least 25-OH-D levels — are known to differ between races and ethnicities, perhaps because of skin color. Although it is possible that study results would hold true for other ethnicities, to date, few related data have been collected, he said. "We need similar studies with other ethnicities, including Japanese."
Dr. Niino agreed with the authors that although the study did not uncover a direct relationship between the 2 MS risk factors investigated, "further prospective studies are needed to investigate potential interactions of vitamin D level and remote EBV infection."
Dr. Chan has disclosed that he received personal compensation as a speaker or consultant for Bayer Schering, Biogen Idec, Merck Serono, Novartis, Sanofi-Aventis, and Teva Neuroscience, as well as research support from the German Ministry for Education and Research (BMBF, German Competence Network Multiple Sclerosis [KKNMS], CONTROL MS, 01GI0914), Bayer Schering, Biogen Idec, Merck Serono, and Novartis. Dr. Niino has disclosed that he receives research support from Grants-in-Aid for Scientific Research from the Ministry of Health, Labor, and Welfare of Japan, and from the National Hospital Organization of Japan; that he serves on a scientific advisory board for Biogen Idec; and that he has received speaker honoraria from Biogen Idec, Bayer Schering Pharma, Asahi Kasei Kuraray Medical Co Ltd, and Novartis Pharma.
J Neurol Neurosurg Psychiatry. Published online August 11, 2012. Abstract
J Neurol Neurosurg Psychiatry. Published online August 20, 2012. Editorial extract
Thursday, July 19, 2012
We Started A Revolution With Just One Shot
Nutri-GenX is Proud to Announce Our Newest
Epigenetic EPX™ Product
Pro NutriShot X is the Next Evolution in Epigenetic Nutritional Products and the Only "EPX" Epigenetic Liquid Supplement Available in the World.
Since we are all going to live longer it might be a good idea to take
better care of ourselves while we are younger. Epigenetics has taught us
that we have the ability to can change our health today by improving
our diets and lifestyles. These changes not only effect us now but they
also have a direct effects on future generations, our children and
grandchildren.We have a chance to not only fight disease but to eradicate it in future generations through nutrition and not drugs. This year over 24.6% of the U.S. Population either have diagnosed or undiagnosed Diabetes and that number continues to grow. It is a stark contrast to the late 1970's when only 3% of the population was diabetic. Through the modern marvels of food science we are now eating foods that may taste great but are poisoning our bodies and that is evident in so many nutritional diseases today. Isn't it time that you decided to make a change and do something that is not only good for you but is also good for the future generations. We can change the downward spiral that mankind is on if we only pay attention today.
Nutri-GenX because of our proprietary MPowered EPX™ designated formulations we help promote proper nutritional utilization by your body. There are be no mega-doses of anything in the EPX™
line of products, just sensible nutrition and supplementation. Nutri-genX has looked beyond the everyday vitamin and mineral
supplement that our parent used, products that offered “a better life
through chemistry" and now we have options that were not available even 2 years ago like Bio-Active, Bio-Available and Bio-Identical Vitamins and Amino Acids, our own LifeDrops™ Standardized Herbal Extracts plus the addition of Mina-GenX™ soluble Minerals and X-Zymes™ Enzymes.
Pro NutriShot X has a great berry flavor "no kidding" it is made with only the finest USDA Certified Organic, or Natural Ingredients available. We are Gluten, Soy, Rice, Dairy, Animal and Nut Free. We use no fillers or colors in our products and only natural sweeteners if needed and only the finest preservatives available for your protection.
Nutrition helps fight: Obesity, Aging, Disease and Stress without making you break a sweat. Pro NutriShot X gives you a gentle boost of energy and a more healthful appearance almost the first time that you use it. Today 80% of the population is deficient in one or more nutrients and that is not because of our poor diets, it because we can't absorb the essential nutrients that our bodies require for us to maintain or health. There are several factors which cause this to occur; Pharmaceutical Drug, Food Additives, Colors, Flavors, Laxative, Antacids, NSAIDS, and that just the beginning because disease like Diabetes and Stress and host of other daily issues adversely effect our health too.
Pro NutriShot X will work for you today and everyday because it was designed to work with your bodies metabolism todays. Yes we live in a stressful and toxic environment but, there is no reason to let it kill you. We can adapt, that what epigenetics is all about.
Nutri-GenX because of our proprietary MPowered EPX™ designated formulations we help promote proper nutritional utilization by your body. There are be no mega-doses of anything in the EPX™
line of products, just sensible nutrition and supplementation. Nutri-genX has looked beyond the everyday vitamin and mineral
supplement that our parent used, products that offered “a better life
through chemistry" and now we have options that were not available even 2 years ago like Bio-Active, Bio-Available and Bio-Identical Vitamins and Amino Acids, our own LifeDrops™ Standardized Herbal Extracts plus the addition of Mina-GenX™ soluble Minerals and X-Zymes™ Enzymes.
We
understand that just one “do it all product” won’t answer all of your problems but it sure will get you started on the right track and it sure beats even nothing or what you are doing now. At Nutri-GenX we have researched and
created a balance or as we say a synergistic fusion between our cutting
edge technology, human physiology and the proper use of amazingly pure Vitamins, Minerals, Standardized Herbal Extracts, Phytonutrients, Amino Acids and Enzymes: in other words our "EPX" designation.
Pro NutriShot X has a great berry flavor "no kidding" it is made with only the finest USDA Certified Organic, or Natural Ingredients available. We are Gluten, Soy, Rice, Dairy, Animal and Nut Free. We use no fillers or colors in our products and only natural sweeteners if needed and only the finest preservatives available for your protection.Nutrition helps fight: Obesity, Aging, Disease and Stress without making you break a sweat. Pro NutriShot X gives you a gentle boost of energy and a more healthful appearance almost the first time that you use it. Today 80% of the population is deficient in one or more nutrients and that is not because of our poor diets, it because we can't absorb the essential nutrients that our bodies require for us to maintain or health. There are several factors which cause this to occur; Pharmaceutical Drug, Food Additives, Colors, Flavors, Laxative, Antacids, NSAIDS, and that just the beginning because disease like Diabetes and Stress and host of other daily issues adversely effect our health too.
Pro NutriShot X will work for you today and everyday because it was designed to work with your bodies metabolism todays. Yes we live in a stressful and toxic environment but, there is no reason to let it kill you. We can adapt, that what epigenetics is all about.
Try it today; It will not only make you feel better,
it will also make you look better too, we guarantee it!
Tuesday, April 24, 2012
Your Toothbrush Can't Do What CavX4 Can
Nutri-GenX™ Has Found A Sweet Solution to an Old Problem, Dry Mouth and the Cavities and Pain it Causes. CavX4™ Oral Spray is the newest product sensation from Nutri-GenX™® and their Ora-GenX™ line of oral products. http://www.StopCavitiesNow.com
CavX4™ Oral Spray provides instant and long lasting relief from the pain and discomfort associated with Dry Mouth and helps correct the problems common to Dry Mouth sufferers ie. sore tongue, cavities, bad breath, cankers, gingivitis and mouth ulcers.
Ora-GenX™ assists in saliva production and provides increased moisture to those with dry mouth. "Tooth decay should be a thing of the past" states Dr. Martin President of Nutri-GenX™® but today tooth decay in children has increased 29% in the past 10 yrs. Experts believe that too many sugary, processed foods and not enough brushing are to blame. But, that is only a part of the story.
Brushing is not to blame because it can’t address the real problem and that is the pH of your mouth. The acidic nature of our diets and the fact people eat all day everyday it is no wonder that our mouths have become nothing but a breeding ground for Streptococcus mutans a gram-positive organism that is the primary causative agent in the formation of dental cavities in humans.
Only the Ora-GenX™ Sensations: CavX4™ Oral Spray, Brushing Gel, Daily Rinse and Night Gel act to help correct this problem and fight Dry Mouth at its source all with a refreshing natural strawberry flavor.Saliva is your bodies natural defense mechanism against cavities. But, what happens when your body falls short and can’t produce the saliva it needs due to age, epigenetics, prescription drugs, disease? Dry Mouth, Cavities, Sore tongue, Pain, Gingivitis, Mouth Ulcers, Bad Breath etc.
Ora-GenX™ is a saliva booster and helps your mouth maintain the correct pH level which in turn fights cavities and helps to maintain a fresh mouth and breath. CavX4™ Oral Spray is all natural, fluoride-free and protects teeth in 4 essential ways.
(1) It helps raise pH levels to neutralize more acid than saliva can alone
(2) Protects tooth enamel by providing a calcium that is very close to tooth enamel
(3) Xylitol fights cavities when combined with saliva and studies show that it my help to remineralize tooth enamel as well
(4) CavX4™ Oral Spray wraps your teeth with a layer of protection helping to safeguard them from decay by using a natural biometric polymer and all natural oral moisturizers.
Use CavX4™ Oral Spray as often as needed for relief, especially at night or as directed by your dentist, hygienist or physician. Spray liberally onto tongue and teeth and spread thoroughly. Effectively helps denture wearers and mouth breathers and smokers too. It’s as easy as Spray, Swish and Swallow.
Relieves dry mouth symptoms caused by: Diabetes, Prescription Medications, Stress & Depression, Drug / Radiation Therapies, Sjogren's Syndrome, Vitamin Deficiencies and even helps prevent and helps to heal mouth sores during Chemotherapy.
Ora-GenX™ is the latest product evolution in the Epigenetic Wellness field created and pioneered by Nutri-GenX™® and Dr. Martin over the past decade.
Epigenetics is the scientific field of study that deals with our common X Factor Epigenetic Chromosomes and our current environment and how we as a species are being effected through the rapid changes that we have created to that environment. Many people fear that those factors are the underlying reason that diseases/conditions like; Autism, Diabetes, Dementia, Parkinson's and many auto immune disorders have been growing at alarming rates over the past 20 years.
According to the US Government statistics in the 1970‘s 3% of the US population had diabetes and in 2011 28.6% of the US population is either diagnosed or undiagnosed with either type 1 or type 2 diabetes.
This trend in now spanning the world throughout cultures once thought to be immune to such diseases due to the rarity seen in their various ethnic haplogroups.http://www.StopCavitiesNow.com
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